About the systematic review:
Inadequate supply of filtering facepiece respirators (FFR) for healthcare workers during a pandemic such as the novel coronavirus outbreak (SARS-CoV-2) is a serious public health issue. A potential approach to extending the use of existing FFRs would be to decontaminate and re-use the masks. To help inform FFR-reuse policies and procedures, our team has conducted three systematic reviews to synthesize existing published data regarding the effectiveness of UVGI, heat, microwave irradiation, and chemical disinfectants for N95 FFR decontamination This review focused on chemical disinfectants, with the following objectives: (1) to assess the impact of each chemical disinfectant on FFR performance, with a specific focus on aerosol penetration and airflow resistance; (2) to determine the effectiveness of decontamination using chemical disinfectants at removing viral or bacterial load; and (3) to describe measures or observations related to fit or physical degradation.